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Assoc. Prof. Michael Uhlin - Centre for allogeneic stem cell Transplantation (CAST) Karolinska University Hospital

Adoptive T cell therapies after allogeneic stem cell transplantation

Time: Thu 2015-05-21 09.00 - 11.00

Location: FA31

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Title: Adoptive T cell therapies after allogeneic stem cell transplantation

Abstract:

Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative treatment for children with therapy-resistant leukemia. The curative effect results from both the radiation and/or chemotherapy in the conditioning regimen and a graft-versus leukemia (GVL) effect of the new donor immune system. Worldwide the number of performed HSCT has over the last two decades increased to over 20 thousand annually. However, the treatment procedure itself is still associated with a substantial mortality risk. During the presentation the experience of Karolinska, Centre for allogeneic stem cell transplantation will be covered regarding different techniques and strategies for adoptive cell therapies after HSCT. Examples will be given for how different separation strategies of cells can be used in order to combat infectious complications and threatening stem cell rejection

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Belongs to: Department of Applied Physics
Last changed: Apr 30, 2015